منابع مشابه
Retroviruses and human disease
Over the past 25 years animal retroviruses have been favoured subjects of research by virologists, oncologists, and molecular biologists. Retroviruses have given us reverse transcriptase, oncogenes, and cloning vectors that may one day be exploited for human gene therapy. They have also given us leukaemia and the acquired immune deficiency syndrome (AIDS). Kawasaki disease and tropical spastic ...
متن کاملRetroviruses and human disease.
Over the past 25 years animal retroviruses have been favoured subjects of research by virologists, oncologists, and molecular biologists. Retroviruses have given us reverse transcriptase, oncogenes, and cloning vectors that may one day be exploited for human gene therapy. They have also given us leukaemia and the acquired immune deficiency syndrome (AIDS). Kawasaki disease and tropical spastic ...
متن کاملHuman retroviruses and paediatric disease.
Retroviruses are a distinct group of RNA viruses which replicate via a double stranded DNA intermediate, synthesised from the virion by an RNA dependent DNA polymerase (reverse transcriptase). Thus unlike other viruses, exogenous RNA codes for DNA. The intermediate, known as the provirus, is integrated into host cell DNA and acts as a template for the production of viral genomic and messenger R...
متن کاملEndogenous Retroviruses and the Human Genome: Implications for Human Disease
Introduction Lifecycle and Genome Organization Endogenization Process and Host-Virus Evolution Classification of HERVs HERV Manipulation of Host Function Host Defenses against HERVs Cancer Multiple Sclerosis Schizophrenia Azoospermia Conclusions Sources Abstract Human endogenous retroviruses (HERVs) constitute approximately 8% of the human genome (16, 22, 39, 55). These ancient retroviruses rep...
متن کاملGlobalization of human infectious disease.
Globalization has facilitated the spread of numerous infectious agents to all corners of the planet. Analysis of the Global Infectious Disease and Epidemiology Network (GIDEON) database quantitatively illustrates that the globalization of human infectious agents depends significantly on the range of hosts used. Infectious agents specific to humans are broadly and uniformly distributed, whereas ...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2005
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.113-a810a